Rife for Lyme Disease. Royal Ramond Rife, a scientist and inventor, invented the Rife Machine in the 1930’s. Interest was regained in the Rife Machine after a book about using a Rife Machine to cure cancer was published. Binding agents are especially integral for those using Biocidin, as the breakdown of biofilms, mycotoxins and pathogens can cause die-off or Herxheimer-type detox reactions. Endotoxins from Gram-negative bacteria such as LPS, heavy metals, and metabolites of yeast, mold or bacteria can all contribute to an increased toxic burden and promote ...